〔Abstract〕 Objective To investigate the traditional Chinese medicine constitution of patients with benign prostatic hyperplasia (BPH), analyze the risk factors leading to the clinical progression of BPH, and propose countermeasures. Methods 202 patients with BPH who came to Zhongshan Chenxinghai Hospital of Integrated Chinese and Western Medicine from January 2021 to December 2023 for physical examination, consultation and hospitalization were selected, and the TCM physique identification of all patients was investigated. In addition, all patients were divided into a progressive group (44 cases) and a non-progressive group (158 cases) to analyze the independent risk factors for clinical progression of BPH. Results 202 cases of BPH patients were mainly characterized by Yang deficiency and Qi deficiency. Multiple logistic regression analysis showed that International Prostate Symptom score (IPSS) > 20, total prostate volume (TPV) > 30 mL and serum total prostate-specific antigen (PSA) level > 1.2 μg·L^-1 were independent risk factors for the clinical progression of BPH (P < 0.05). Conclusion The identification of traditional Chinese medicine constitution of BPH patients is mainly dominated by Yang deficiency and Qi deficiency. IPSS score > 20, TPV level > 30 mL, and serum total PSA level > 1.2 μg·L^-1 are independent risk factors for the clinical progression of BPH. Medical staff can take effective measures according to the above indicators. To reduce the probability of clinical progression of BPH.