〔Abstract〕 Diabetes peripheral neuropathy(DPN) is one of the common clinical complications of diabetes. Its onset and development are very secret. It is characterized by sensory abnormalities, sensory loss and pain. it is a neuropathy caused by changes in metabolism and microvascular factors. Chief Physician Huang Xiangwu believes that the etiology and pathogenesis of the disease are mainly due to chronic thirst quenching, yin and yang loss over time, kidney yang deficiency, deficiency of yang qi, and the external cold evil qi. The guest is in the pulse, and the blood coagulates when it encounters cold; In addition, Yang Qi is weak, blood circulation is not smooth, and it can not reach the end of the limbs, then the temperature of the four fingers drops, and the disease is caused by lack of nourishing. It should be treated by warming the kidney to help Yang, promoting blood circulation and removing blood stasis, and the self prepared formula for warming Yang and removing blood stasis is very effective in clinical application.