〔Abstract〕 Objective To explore the effect of acupoint injection of glucose on functional recovery of joint stiffness caused by neuropathic pain after knee arthroscopy and reduction of oral dose of gabapentine capsule. Methods Fifty patients with joint stiffness caused by neuropathic pain after knee arthroscopy admitted to Guizhou Provincial Orthopaedic Hospital from January 2020 to January 2023 were randomly divided into an observation group and a control group, with 25 cases in each group. On the basis of comprehensive rehabilitation treatment and oral gabapentin capsule, the observation group received 5% glucose injection around the knee, and the control group was treated with 0.9% sodium chloride injection. The degree of knee pain, knee motion and quality of life were compared between the two groups. Results After 5 weeks of treatment, The visual analogue scale (VAS) score and daily dose of oral gabapentin capsule in the observation group were lower than those in the control group, with statistical significances (P < 0.05). After 5 weeks of treatment, the knee-joint active range of motion (AROM) and the scores of 36-item short form health survey (SF-36) in the observation group were higher than those in the control group, with statistical significances (P < 0.05). Conclusion Acupoint injection of glucose can accelerate the functional recovery of joint stiffness caused by neuropathic pain after knee arthroscopy and reduce the oral dose of gabapentin capsule.