〔Abstract〕 Objective To analyze the clinical value of modified Qianghuo Shengshi decoction combined with intermediate frequency pulse electrotherapy in the treatment of cervical spondylosis. Methods A total of 96 patients with cervical spondylosis from Xuchang People’s Hospital between August 2021 and October 2022 were selected and divided into a combined group (48 cases) and a single treatment group (48 cases) according to a random number table. Patients in the single treatment group were treated with intermediate frequency pulse electrotherapy, while patients in the combined group were additionally treated with modified Qianghuo Shengshi decoction on the basis of the single treatment group. The clinical efficacy, time for symptoms to resolve (neck mobility restriction, neck stiffness, aversion to cold), numerical rating scale (NRS) for pain, cervical function scores [neck disability index (NDI), cervical range of motion (CROM)], levels of inflammatory factors [interleukin-6 (IL-6), IL-1β, tumor necrosis factor-α (TNF-α)], and the incidence of adverse reactions were compared between the two groups. Results The combined group showed a higher total effective rate than the single treatment group. The time for symptoms to resolve, including neck mobility restriction, neck stiffness, and aversion to cold, was shorter in the combined group than that in the single treatment group. After one and two courses of treatment, the NRS scores were lower in the combined group compared to the single treatment group. After treatment, the NDI score was lower and the CROM score was higher in the combined group than that in the single treatment group. Additionally, the serum levels of IL-6, IL-1β, and TNF-α were lower in the combined group than those in the single treatment group, with statistically significant differences (P < 0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P > 0.05). Conclusion The treatment of cervical spondylosis with modified Qianghuo Shengshi decoction combined with intermediate frequency pulse electrotherapy can enhance clinical outcomes, reduce the time for symptoms to resolve, alleviate pain, promote the recovery of cervical function, reduce inflammatory responses, and has good safety.