Abstract:〔Abstract〕 Objective To investigate the recurrence of postoperative stone in patients with intrahepatic and intrahepatic bile duct stones and analyze the risk factors of stone recurrence. Methods The study population comprised 78 patients with intrahepatic and extrahepatic bile duct stones who were diagnosed and treated at Tongbai County People’s Hospital from March 2019 to January 2022. All patients underwent laparoscopic left hemihepatectomy. Data on short-term prognosis and recurrence during follow-up were recorded, and the risk factors for recurrence in these patients were analyzed. Results All patients were followed up for 1 year after surgery, and 10 of 78 patients had relapse (relapse group), the recurrence rate was 12.82%. Univariate analysis showed that the Child grade, disease course, multiple stones and maximum stone diameter in the recurrence group were significantly different from those in the non-recurrence group (P < 0.05). Multivariate logistic regression analysis showed that Child grade B, disease duration ≥ 3 months, multiple stones and maximum stone diameter ≥ 1.25cm were risk factors for postoperative stone recurrence in patients with intrahepatic and intrahepatic bile duct stones (P < 0.05). Conclusion Postoperative stone recurrence is still relatively high in patients with intrahepatic and intrahepatic bile duct stones. Child grade B, disease duration ≥ 3 months, multiple stones, and maximum stone diameter ≥ 1.25cm are independent risk factors for recurrence. Patients who meet one or more of these criteria should be paid attention to to ensure the effect of surgery.