〔Abstract〕 Objective To analyze the clinical effects of perioperative nursing for patients undergoing external inversion procedure for breech position in late pregnancy. Methods A total of 80 patients with breech position in late pregnancy were selected from Shangyou County Maternal and Child Health Care Hospital from January 2021 to June 2023 as the observation subjects, all underwent external breech inversion surgery, and they were randomly divided into a control group and an observation group, with 40 cases in each group. The control group received routine nursing, while the observation group received perioperative nursing. The surgical stress and quality of life of the two groups of patients were evaluated. Results After the surgery, the systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), and oxygen saturation (SPO₂) of the two groups increased. Compared with the control group, the SBP, DBP, MAP, and HR of the observation group were lower, and the SPO₂ was higher, with statistically significant differences (P < 0.05). After the surgery, the scores of physiological function, physical role, vitality, social function, emotional role, and mental health of both groups increased. Compared with the control group, the observation group had higher scores in the physiological function, physical role, vitality, social function, emotional role, and mental health, with statistically significant differences (P < 0.05). Conclusion The application of perioperative nursing for patients undergoing external inversion procedure for breech position in late pregnancy can reduce the surgical stress to a certain extent and improve the quality of life of patients.