Abstract:〔Abstract〕 Objective To analyze the digestive tract symptoms and laboratory indexes of elderly and non-elderly patients with corona virus disease 2019 (COVID-19). Methods Seventy-nine patients with mild and common COVID-19 admitted to Shenzhen Dapeng New District Kuichong People's Hospital from December 2022 to January 2023 were selected retrospectively. According to their age, they were divided into elderly group ( ≥ 60 years old, 35 cases ) and non-elderly group (< 60 years old, 44 cases), and the digestive tract symptoms and laboratory indexes of the two groups were compared. Results The difference in symptoms of decreased appetite between the two groups was statistically significant (P < 0.05). There was no statistically significant difference in the symptoms of abdominal distension, nausea, abdominal pain and diarrhea between the two groups of patients (P > 0.05). There was no statistically significant difference in indicators such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin indirect bilirubin, and direct bilirubin between the two groups of patients (P > 0.05). There was no statistically significant difference in the levels of C-reactive protein (CRP) and lactate dehydrogenase (LDH) between the two groups (P > 0.05). The comparison of creatinine in the elderly group showed that higher than than of the non-elderly group, and the difference was statistically significant (P < 0.05),but the average is still within the normal range. The incidence of fecal occult blood positivity in the elderly group was 14.28% (5/35), while the incidence in the non-elderly group was 18.18% (8/44), with no statistically significant difference (P > 0.05). The serum albumin level in the elderly group was significantly lower than that in the non-elderly group, and the difference was statistically significant (P < 0.05). Conclusion In patients with mild and common COVID-19, there is no obvious difference in infection, biochemistry and other indicators between the elderly group and the non-elderly group, but the elderly group has a higher probability of developing digestive tract symptoms, and the serum albumin content is significantly decreased. The occurrence of gastrointestinal symptoms such as decreased appetite in the elderly group may be one of the important reasons for the decrease of serum albumin in this group of patients.