〔Abstract〕 Objective To observe the clinical effect of Maxing Shedan decoction combined with western medicine on bronchial asthma. Methods A total of 80 patients with bronchial asthma admitted to Zhangzhou Changtai District Hospital from January 2021 to January 2023 were selected and divided into two groups, with 40 cases in each group by random number table method. The control group was treated with western medicine, and the observation group was treated with Maxing Shedan decoction combined with Western medicine. The scores of traditional Chinese medicine (TCM) symptoms, sleep disorder scores, disease rehabilitation correlation indexes before and after treatment and therapeutic effects of the two groups were compared. Results After treatment, the TCM symptom score and sleep disorder score in the observation group were lower than those in the control group, the differences were statistically significant (P < 0.05). The symptoms of cough, dyspnea and pulmonary wheezing in the observation group were significantly reduced and disappeared for a shorter time than those in the control group, the differences were statistically significant (P < 0.05). The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P < 0.05). Conclusion The combination of Maxing Shedan decoction and Western medicine can alleviate the severity of symptoms and sleep disorders in patients with bronchial asthma, and shorten the recovery time of the patient's condition.