〔Abstract〕 Objective To investigate the results of 12-lead synchronous electrocardiogram in patients with acute myocardial infarction (AMI) complicated with ventricular arrhythmia and ventricular remodeling. Methods Sixty-two AMI patients admitted to Longyan First Hospital from January 2021 to December 2022 who received 12-lead synchronous electrocardiogram monitoring within 24 hours of admission were selected for echocardiography. According to whether ventricular arrhythmias occurred, the patients were divided into a non-ventricular arrhythmias group (22 cases) and a ventricular arrhythmias group (40 cases). According to whether ventricular remodeling occurred, the patients were divided into a ventricular remodeling group (24 cases) and a nonventricular remodeling group (38 cases). The ECG indexes of patients with ventricular arrhythmia, ventricular remodeling and adverse cardiovascular events were analyzed and compared. Results The levels of Tp-Te, corrected Tp-Te Interval (Tp-Tec) and Tp-Te/QT in the ventricular arrhythmia group were higher than those in the non-ventricular remodeling group, and the differences were statistically significant (P < 0.05). The levels of Tp-Te, Tp-Tec and Tp-Te/QT in the ventricular remodeling group were higher than those in the non-ventricular remodeling group, and the difference were statistically significant (P < 0.05). The levels of Tp-Te, Tp-Tec and Tp-Te/QT in the patients with adverse cardiovascular events were higher than those in the patients with non-ventricular arrhythmias, and the differences were statistically significant (P < 0.05). Conclusion For AMI patients with ventricular arrhythmia and ventricular remodeling, the 12-lead synchronous electrocardiogram index is worse, and the TP-TE interval has predictive value for the prognosis of AMI.