〔Abstract〕 Objective To investigate the effects of leonurus granules on the levels of inflammatory factors and microcirculation in induced abortion patients. Methods A total of 90 patients who underwent artificial abortion in Zhengzhou Guancheng Hospital of Traditional Chinese Medicine from January 2022 to January 2023 were randomly divided into an observation group and a control group, with 45 patients in each group. The control group was treated with routine treatment after artificial abortion, and the observation group was treated with leonurus granules on the basis of the control group. The changes of uterine bleeding time, blood loss, blood routine indexes, cervical mucus inflammatory factors and microcirculation indexes were compared between the two groups. Results The time and amount of uterine bleeding in the observation group were less than those in the control group, and the differences were statistically significant (P < 0.05). After operation, the levels of hemoglobin and erythrocyte in the observation group were higher than those in the control group, the differences were statistically significant (P < 0.05). After operation, the levels of interleukin (IL)-1, IL-6 and tumor necrosis factor-α (TNF-α) in the observation group were lower than those in the control group, and the levels of IL-2, IL-10 and IL-4 were higher than those in the control group, with statistical significance (P < 0.05). After operation, the capillary flow velocity of the observation group was higher than that of the control group, and the red blood cell aggregation index, white microthrombus, periloop and tube loop morphology scores were lower than those of the control group, with statistical significance (P < 0.05). Conclusion After artificial abortion, the use of leonurus granules in patients can help regulate and improve the inflammatory condition of the body, promote the removal of microcirculation obstacles, effectively inhibit uterine bleeding, and further reduce the incidence of cervical adhesion and other complications.