〔Abstract〕 Objective To compare the medium and long-term efficacy of Corail hydroxyapatite fully coated femoral stem prosthesis (Corail prosthesis) and Summit semi coated femoral stem prosthesis (Summit prosthesis) in patients undergoing total hip arthroplasty (THA). Methods Retrospective analysis was made on 32 patients who underwent THA in articular bone surgery department of the First People's Hospital of Foshan from August 2018 to February 2020. According to the type of femoral stem prosthesis used in the surgery, the patients were divided into an observation group (Corail prosthesis) with 17 cases and a control group (Summit prosthesis) with 15 cases. The surgery was completed by the same group of operators, and the prosthesis was placed in the correct position. The postoperative rehabilitation plan was the same. During 1 day, 3 days, 1 week, 3 weeks, 1 month, 3 months, 6 months, 9 months, and 1 year after surgery, patients were followed up in the hospital and outpatient department to compare the surgical blood loss, incision length, clinical efficacy, discharge time, Harris score before and after surgery, and visual analogue scale (VAS) score between the two groups of patients. Results The wounds of 32 patients healed in Grade A, and no patients needed revision in the first year after operation. There was no significant difference in perioperative related indexes between the two groups (P > 0.05) . All patients had an increase in the Harris score postoperatively compared with preoperatively and with time, as well as a decrease in the VAS score, as compared between the two groups, there was no significant difference between the two groups (P > 0.05), 4 cases in the control group showed clear line and 2 cases in the observation group showed bone subsidence but no loosening when the imaging examinations were performed one year after operation, there were no osteolysis, loosening of prosthesis, infection and fracture around prosthesis in both groups, and the survival rate of prosthesis was good. Conclusion There is no significant difference in the recovery effect between Corail and Summit prostheses in THA patients in the medium to long term after surgery. The changes in postoperative imaging between the two types of prostheses are not significant, and patients can achieve good fixation after surgery.