腹腔镜手术与传统开腹术治疗异位妊娠术后 患者妊娠率与再发异位妊娠率比较
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侯明雅,女,主治医师,主要从事妇产科的工作。

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R 714.2

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Pregnancy Rate and Recurrence Rate of Patients after Laparoscopic Surgery and Traditional Laparotomy for Ectopic Pregnancy
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    摘要:

    摘 要目的:研究腹腔镜手术与传统开腹术治疗异位妊娠术后患者妊娠率与再发率情况。 方法:回顾性选取 2019 年 1 月至 2021 年 10 月在晋江市妇幼保健院接受手术治疗的异位妊娠患者资料,根据手术方式将采用传统开腹 术治疗的 49 例患者纳入开腹组,采用腹腔镜手术治疗的 49 例患者纳入腹腔镜组。比较两组患者临床指标,观察术前、 术后 3 d 两组患者血清炎症因子水平的变化,统计两组患者术后不良反应发生率,术后随访 1 年统计两组患者妊娠率 与再发异位妊娠率。 结果:两组患者人绒毛膜促性腺激素(HCG)转阴时间比较,差异无统计学意义(P > 0.05)。 与开腹组患者比较,腹腔镜组患者术后各项恢复进程短;腹腔镜组患者术后 3 d 血清 C 反应蛋白(CRP)、白细胞介 素(IL)–6、IL–1β 水平低;腹腔镜组患者术后并发症发生率低;术后 1 年,腹腔镜组患者输卵管畅通率、宫内妊娠 率高,差异具有统计学意义(P < 0.05)。 结论:腹腔镜手术治疗异位妊娠能够提高患者术后远期输卵管畅通率从而 获得更高的术后妊娠率,但再发异位妊娠率与开腹术未见明显差异。

    Abstract:

    AbstractObjective To study the pregnancy rate and recurrence rate of ectopic pregnancy patients after treatment by laparoscope surgery and traditional laparotomy. Methods Data of ectopic pregnancy patients who received surgical treatment in Jinjiang Maternal and Child Health Hospital from January 2019 to October 2021 were retrospectively selected. According to the surgical method, 49 patients who received traditional laparotomy were included in the laparotomy group, and 49 patients who received laparoscopic surgery were included in the laparoscopic group. The clinical indexes of the two groups were compared, and the changes of serum inflammatory factors in the two groups were observed before and 3 days after surgery, and the incidence of postoperative adverse reactions in the two groups were analyzed. The pregnancy rate and recurrent ectopic pregnancy rate of the two groups were analyzed after 1 year follow-up. Results There was no significant difference in the conversion time of human chorionic gonadotropin (HCG) between the two groups (P > 0.05). Compared with the laparotomy group, the postoperative recovery process in the laparoscopic group was shorter, the levels of serum C-reactive protein (CRP), interleukin (IL)-6 and IL-1β were lower in the laparoscopic group 3 days after operation, the incidence of postoperative complications was lower in the laparoscopic group, and the differences were statistically significant (P < 0.05). One year after surgery, the rate of tubal patency and intrauterine pregnancy in the laparoscopic group were higher, and the differences were statistically significant (P < 0.05). Conclusion Laparoscopic surgery for ectopic pregnancy can improve the long-term fallopian tube patency rate after surgery to obtain a higher postoperative pregnancy rate, but there is no significant difference in the probability of recurrent ectopic pregnancy compare with traditional laparotomy.

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  • 收稿日期:2023-02-10
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  • 在线发布日期: 2023-07-10
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