〔Abstract〕 Post-stroke cardiac dysfunction is a common clinical phenomenon. In the early stages of stroke, it frequently manifests as cerebral cardiac syndrome, while during the recovery period, it is predominantly characterized by reduced cardiopulmonary endurance. Cardiac rehabilitation in stroke patients has been demonstrated to be effective in preventing and reversing these deleterious health outcomes, thereby reducing the risk of recurrent stroke or mortality and carrying significant clinical significance. However, the current models for post-stroke cardiac rehabilitation remain in the exploratory stage. Notably, research has primarily focused on individuals with mild to moderate motor impairments, while patients with severe motor impairments who lack ambulatory capacity have received limited attention. The authors perform a systematic review of relevant advances in poststroke cardiac rehabilitation for patients with severe motor impairments, synthesizing findings from both domestic and international research. In order to provide valuable insights into enhancing the cardiovascular health of this patient population.