〔Abstract〕 Objective To investigate the status of discharge readiness of patients after coronary artery bypass grafting (CABG) and analyze its influencing factors. Methods A total of 179 patients with CABG in the 7th People’s Hospital of Zhengzhou from November 2019 to November 2021 were selected as the research objects, the status quo of discharge readiness and influencing factors were analyzed. Results The score of quality of discharge teaching scale (QDTS) was (131.26 ± 15.64). Univariate analysis showed that educational level, payment method of medical expenses, marital status, medication type, self-efficacy score and QDTS score were the factors affecting the discharge readiness of patients after CABG surgery (P < 0.05). Multivariate logistic regression analysis showed that unmarried patients, more than 2 types of medication, low self-efficacy score and low QDTS score were independent risk factors affecting the discharge readiness of patients after CABG surgery (P < 0.05). Conclusion Unmarried patients, more than 2 types of medication, low self-efficacy score and low QDTS score are independent risk factors affecting the discharge readiness of patients after CABG surgery. There are still deficiencies in the personal status of patients in the discharge readiness after CABG surgery. It is necessary to strengthen the assessment and intervention of patients' personal status to further improve the discharge readiness of patients and promote postoperative rehabilitation of patients.