〔Abstract〕 Objective To observe the effect of gardening workshop on female schizophrenics with different early efficacy. Methods A total of 132 female schizophrenics who received treatment in Fuzhou Neuropsychiatric Hospital from October 2020 to July 2021 were selected and randomly divided into a control group and an observation group, with 66 cases in each group. The control group was given routine treatment and nursing, and the observation group was given gardening workshop nursing on the basis of the control group. According to the reduction rate of the second week brief psychiatric rating scale (BPRS) score, the control group and the observation group were classified respectively for statistical analysis, to evaluate the influence of the intervention on the patients with different early efficacy. Results At the end of 2, 4 and 6 weeks after enrollment, the scores of BPRS, personal and social performance scale (PSP) and nursing observation rating scale (NORS) in the two groups were improved compared with those at enrollment, and the scores of BPRS and NORS in the observation group were lower than those in the control group, while PSP score was higher than that in the control group, the differences were statistically significant (P < 0.05). At the end of 2, 4 and 6 weeks after enrollment, BPRS scores of early improvement patients in the two groups were lower than those in the group, and the difference was statistically significant (P < 0.05). At the end of 2, 4 and 6 weeks after enrollment, PSP score of the observation group was higher than that of the control group, and NORS score was lower than that of the control group, the differences were statistically significant (P < 0.05). The BPRS scores of the two groups without early improvement were lower than those of the control group at 4 and 6 weekends after enrollment, while the BPRS scores of the observation group were lower at 2, 4 and 6 weeks after enrollment, the differences were statistically significant (P < 0.05). PSP scores of the two groups with no early improvement were higher at 4 and 6 weeks after enrollment, the differences were statistically significant (P < 0.05). The NORS score of the two groups was lower than that of the group at the 4th and 6th weekend after enrollment, and the NORS score of the observation group was lower than that of the control group at the 2nd, 4th and 6th weekend after enrollment, the differences were statistically significant (P < 0.05). Conclusion Gardening workshop intervention can promote the recovery of mental symptoms, improve social function, improve self-care ability.