妊娠期糖尿病常见影响因素及对母婴结局的影响
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王珺,女,主治医师,主要从事妇产科工作。

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R 714.25;R 587.1

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Analysis of Common Influencing Factors of Gestational Diabetes Mellitus and Its Influence on Maternal and Infant Outcomes
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    摘要:

    摘 要目的:分析妊娠期糖尿病常见影响因素及对母婴结局的影响。 方法:回顾性将 2020 年 1 月至 2022 年 1 月 福建医科大学附属第二医院收治的 117 例妊娠期糖尿病孕妇设为观察组,并选择同期 121 例体检的健康孕妇设为 对照组。比较两组孕妇的一般资料,分析妊娠期糖尿病的常见影响因素和母婴结局。 结果:经单因素分析,年龄、 孕妇类型、孕前体质量指数(BMI)、孕期体质量增加以及糖尿病家族史均为妊娠期糖尿病的影响因素(P < 0.05); 多因素 logistic 回归分析结果显示,年龄≥ 35 岁、经产妇、孕前 BMI ≥ 24 kg·m-2、孕期体质量增加≥ 20 kg 以及伴 有糖尿病家族史是妊娠期糖尿病的独立危险因素(P < 0.05);观察组剖宫产、羊水过多、产后出血、早产、巨大儿、 胎儿窘迫发生率均明显更高于对照组,差异均具有统计学意义(P < 0.05)。 结论:妊娠期糖尿病常见影响因素包括 年龄≥ 35 岁、经产妇、孕前 BMI ≥ 24 kg·m-2、孕期体质量增加≥ 20 kg 以及伴有糖尿病家族史,上述因素均可增 加不良母婴结局的发生风险。

    Abstract:

    AbstractObjective To analyze the common influencing factors of gestational diabetes and their effects on the maternal and infant outcomes. Methods 117 pregnant women with gestational diabetes admitted to the Second Affiliated Hospital of Fujian Medical University from January 2020 to January 2022 were retrospectively set as the observation group, and 121 healthy pregnant women who underwent physical examination in the same period were selected as the control group. The general data of the two groups of pregnant women were compared, and the common influencing factors of gestational diabetes and the maternal and infant outcomes were analyzed. Results By single factor analysis, age, type of pregnant women, BMI before pregnancy, increase of body mass during pregnancy and family history of diabetes were all influencing factors of gestational diabetes (P < 0.05); Multivariate logistic regression analysis showed that the independent risk factors of gestational diabetes were age ≥ 35 years old, multiparous women, pregnancy precursor mass index (BMI) ≥ 24 kg·m-2, pregnancy weight increase ≥ 20 kg, and family history of diabetes (P < 0.05); The incidence of cesarean section, polyhydramnios, postpartum hemorrhage, premature delivery, macrosomia and fetal distress in the observation group was significantly higher than that in the control group (P < 0.05). Conclusion The common influencing factors of gestational diabetes include age ≥ 35 years old, multipara, pre pregnancy BMI ≥ 24 kg·m-2, pregnancy weight increase ≥ 20 kg, and family history of diabetes. These factors can increase the risk of adverse maternal and infant outcomes.

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  • 收稿日期:2022-12-21
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  • 在线发布日期: 2023-06-12
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