〔Abstract〕 ObjectiveTo explore the clinical effect of warm acupuncture and moxibustion combined with warm Jing Sanhan Tongluo decoction on patients with cold and dampness obstruction syndrome of lumbar disc herniation and the influence on traditional Chinese medicine (TCM) symptom integration and lumbar function. Methods A total of 122 patients with cold and dampness obstruction syndrome of lumbar disc herniation who received treatment in Xiamen Jimei District Houxi Town Health Center from January 2020 to January 2022 were selected and randomly divided into an observation group and a control group, 61 cases in each group. The control group received warm acupuncture treatment, and the observation group was treated with warm Jing Sanhan Tongluo decoction on the basis of the control group. The clinical symptoms, joint motion, Japanese Orthopaedic Association (JOA) score, visual analog scale (VAS) score, levels of inflammatory factors and therapeutic effect were compared between the two groups before and after treatment. Results After treatment, the scores of insomnia, leg pain, fatigue, low back pain, irritability, sweating and other symptoms in the observation group were lower than those in the control group, the differences were statistically significant (P < 0.05). After treatment, the joint motion and JOA score of the observation group were higher than those of the control group, while the VAS score of the observation group was lower than that of the control group, the differences were statistically significant (P < 0.05). After treatment, the serum levels of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in the observation group were lower than those in the control group, and the differences were statistically significant (P < 0.05). The total effective rate of the observation group was 98.36 %, higher than 85.25 % of the control group, and the difference was statistically significant (P < 0.05). Conclusion For patients with cold and dampness obstruction syndrome of lumbar disc herniation, warm acupuncture and moxibustion combined with warm Jing Sanhan Tongluo decoction has a good effect, which can improve the clinical symptoms of patients and significantly reduce the inflammatory response.