〔Abstract〕 Objective To analyze the feasibility of intrauterine hemostatic sac reduce the amount of bleeding in nonplacenta previa cesarean section. Methods A total of 90 patients with bleeding > 700 mL during non-placenta previa cesarean section admitted to Fuqing Third Hospital from January 2017 to December 2021 were selected. According to different hemostasis regimens, the patients were divided into a control group (drug hemostasis) and an observation group (drug hemostasis combined with intrauterine hemostatic sac), with 45 cases in each group. The bleeding situation, hemostatic indicators, related complications and prognosis were compared between the two groups. Results The amount of vaginal bleeding at 4 h and 12 h after treatment in the observation group were less than those in the control group, and the hemostasis time was shorter than that in the control group, and the differences were statistically significant (P < 0.05). The incidence of poor prognosis in the observation group was lower than that in the control group, and the difference was statistically significant (P < 0.05). The epinephrine and cortisol of the observation group were lower than those of the control group 24 hours after operation, and the differences were statistically significant (P < 0.05). Conclusion In non-placenta previa cesarean section, the intrauterine hemostatic sac can ensure the hemostasis as soon as possible to control the bleeding volume, shorten the bleeding time, and has a positive effect on the improvement of prognosis, and the use of safety is ideal.