〔Abstract〕 Objective To analyze the diagnostic value of magnetic resonance imaging (MRI) for supratentorial intraparenchymal cystic solid tumor in children and adolescents. Methods The clinical date of 46 supratentorial parenchymal cystic solid tumor of children and adolescents admitted to Kaifeng Central Hospital and Provincial Hospital Affiliated to Shandong First Medical University from June 2014 to May 2021 were collected, and MRI features were analyzed retrospectively. Results All lesions were cystic and solid. Among the 46 tumors, ganglioglioma (GG) 13 cases, pilocytic astrocytoma (PA) 8 cases, pleomorphic xanthoastrocytoma (PXA) 9 cases, dysembryoplastic neuroepithelial tumors (DNET) 4 cases, ependymoma 8 cases, atypical teratoid/ rhabdoid tumor (AT/RT) 3 cases, desmoplastic infantile tumor (DIT) 1 case. Conclusion The morbidity of supratentorial brain parenchymal cystic solid tumors of children and adolescents is low and clinical symptoms are not specific. MRI can better display the location, size, morphology and boundary of tumor, signal characteristics, enhancement characteristics of cyst wall and solid components, peritumoral edema, mass effect and metastasis, typical imaging manifestations of tumors have certain characteristics, but the untypical manifestations are easy to be misdiagnosed. Understanding and mastering the MRI features are helpful for improving of diagnostic accuracy.