〔Abstract〕 Objective To explore the therapeutic effect of acupuncture combined with traditional Chinese medicine (TCM) of the Methods of Jianpi Wenshen on simple obesity with Pishen Yangxu symptom. Methods A total of 120 obese patients with Pishen Yangxu symptom admitted to Luoyang Central Hospital Affiliated to Zhengzhou University from May 2017 to May 2019 were selected and divided into control group (the methods of Jianpi Wenshen treatment) and observation group (acupuncture plus the methods of Jianpi Wenshen treatment) according to different treatment methods, with 60 cases in each group. The changes of body mass, body mass index (BMI), waist-hip ratio (WHR), blood lipid level and TCM syndrome score were observed before and after treatment in the two groups, and the clinical efficacy was compared. Results The total effective rate of the observation group was 93.33%, higher than 71.66% of the control group, the difference was statistically significant (P < 0.05). After treatment, body mass, BMI and WHR of patients in the two groups decreased to varying degrees, and body mass, BMI and WHR of patients in the observation group were lower than those in the control group, the differences were statistically significant (P < 0.05). After treatment, total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) in the observation group were decreased to varying degrees, while high-density lipoprotein cholesterol (HDL-C) increased to varying degrees. TC, TG and LDL-C in the observation group were lower than those in the control group, HDL-C was higher than that in the control group. The differences were statistically significant (P < 0.05). After treatment, the TCM syndrome score of the two groups decreased to varying degrees, and the TCM syndrome score of the observation group was lower than that of the control group, the difference was statistically significant (P < 0.05). Conclusion Acupuncture combined with the methods of Jianpi Wenshen treatment has a good effect in the treatment of simple obesity with Pishen Yangxu symptom. It can reduce body mass, BMI and WHR, and improve blood lipid and TCM syndrome score.