〔Abstract〕 Objective To study the evaluation effect of musculoskeletal ultrasound in chronic plantar fasciitis. Methods A total of 60 patients with unilateral chronic plantar fasciitis admitted to Zhengzhou Orthopedics Hospital from February 2018 to February 2020 were selected as the research objects. The plantar fascia of the affected side and the healthy side were measured by musculoskeletal ultrasound, and then magnetic resonance imaging (MRI) was performed to compare the data differences of the two examination methods on the plantar fascia of both sides. Results There was no significant difference in the reliability between the two methods (P > 0.05); There was no statistical significance in the reliability of the affected side compared with the healthy side (P > 0.05). In the two measurements, the thickness of plantar fascia on the affected side was thicker than that on the healthy side, the difference was statistically significant (P < 0.05). There was no significant difference between the two methods in the measurement results of plantar fascia thickness on the affected side and the healthy side (P > 0.05). Conclusion In the diagnosis of chronic plantar fasciitis, musculoskeletal ultrasound can be used to measure the thickness of plantar fasciitis and evaluate the severity of fasciitis. Although the clarity is not as good as MRI, the measurement results are basically consistent with MRI.