〔Abstract〕Objective To investigate the effect of laser combined with photon in the treatment of facial skin aging and pigmentation. Methods The study subjects were 80 patients with facial skin aging treated in Jiamusi Central Hospital from October 2018 to October 2019 and they were numbered in order of treatment. The odd number as the control group and the even number as the observation group, with 40 patients in each group. The control group was only received with laser, and the observation group was received with photon treatment on the basis of the control group. The improvement of facial skin and pigmentation after treatment between the two groups was compared. Results The total effective rates of facial skin pores, fine lines and compactness in the observation group were higher than those in the control group, and there were significant differences between the two groups (P < 0.05). The total effective rate of facial pigmentation treatment in the observation group was significantly higher than that in the control group, and the difference was statistically significant (P < 0.05). Conclusion For patients with aging facial skin, the treatment effect of laser combined with photon is better, which can improve the facial skin condition of patients and relieve pigment deposition.