〔Abstract〕Objective To study the predictive role of four-dimensional ultrasound for recurrence of pelvic organ prolapse (POP) patients after laparoscopic minimally invasive surgery. Methods A retrospective analysis was performed on the clinical data of 40 patients with POP treated in the First Affiliated Hospital of Gannan Medical College from February 2019 to September 2020. All patients underwent pelvic three-dimensional and four-dimensional ultrasound examinations. The examination results were named as 3D group and 4D group, respectively. Results The total detection rate in 4D group (100.00%) was higher than 87.50% in the 3D group, the difference was statistically signficant (P < 0.05). The specificity and accuracy of predicting POP recurrence in the 4D group were significantly higher than those in the 3D group, the differences were statistically signficant (P < 0.05). Conclusion Compared with three-dimensional ultrasound, four-dimensional ultrasound can more accurately identify the severity of POP symptans in patients, and its sensitivity, accuracy and specificity are higher in predicting recurrence after laparoscopic minimally invasive surgery.