〔Abstract〕Objective To observe the effect of Traditional Chinese Medicine (TCM) syndrome dialectical nursing auxiliary drug treatment on the treatment compliance and clinical effect of children with sudden deafness. Methods A total of 68 children with sudden deafness admitted to Nanyang Central Hospital from March 2018 to October 2020 were selected and randomly divided into control group and observation group, with 34 cases in each group. The control group was given alprostadil intravenous drip plus oral mecobalamin plus basic nursing, while the observation group was given reed tube moxibustion, drumming, ear acupoint pressing, tympanic membrane massage, life, diet, and emotional TCM syndromes dialectical nursing on the basis of the control group. The improvement of pure tone hearing threshold and impaired frequency hearing threshold, clinical efficacy and children's treatment compliance were compared between the two groups before and after the intervention. Results After 14 days of drug treatment and dialectical nursing, the total effective rate of children in the observation group was 94.12 %, which was higher than 70.59 % in the control group, and the difference was statistically significant (P < 0.05). After intervention, the pure tone hearing threshold and impaired frequency hearing threshold of the observation group were lower than those of the control group, and the differences were statistically significant (P < 0.05). The treatment compliance of children in the observation group was 97.06%, which was significantly higher than 76.47% in the control group, and the difference was statistically significant (P < 0.05). Conclusion TCM syndrome differentiation nursing auxiliary drug treatment can effectively improve the treatment compliance of children with sudden deafness, improve the curative effect, and promote hearing recovery