〔Abstract〕 Objective To investigate the value of digital reduction angiography (DSA) in intracranial complex aneurysm intervention hybrid surgery. Methods The clinical data, examination methods, treatment methods, and treatment results of 20 cases of intracranial complex aneurysms in Zhengzhou First People's Hospital from May 2017 to May 2019 were analyzed retrospectively. Results 20 patients underwent 2D-DSA before 3D-DSA. There was no significant difference in the detection rate between 2D-DSA and 3D-DSA (P > 0.05). The angiographic evaluation score of 3D-DSA was higher than that of 2D-DSA, and the difference was statistically significant (P < 0.05). The operations of 20 patients were successfully completed; the patients were followed up for 8 to 30 months, and the aneurysms disappeared. Conclusion DSA technology can assist in surgical treatment, enhance the safety of treatment and has high application value in the evaluation of prognosis.