Abstract:〔Abstract〕 Objective To explore the effect of Traditional Chinese medicine compound Xueyaning recipe on blood pressure variability in elderly patients with hypertension. Methods A total of 80 elderly hypertensive patients who were admitted to Liuyang Hospital of Traditional Chinese Medicine from August 2017 to August 2018 were selected and divided into observation group and control group, with 40 cases in each group. Patients in the observation group were treated with benazepril combined with amlodipine and treated with traditional Chinese medicine at the same time, and the control group was treated with benazepril combined with amlodipine, the blood pressure variability and the incidence of adverse reactions were compared between the two groups. Results There was no significant difference in blood pressure variability between the two groups of patients before treatment (P > 0.05). After treatment, the blood pressure variability of the observation group was lower than that of the control group, the difference was statistically significant (P < 0.05). The incidence of adverse reactions in the observation group was 5.00% lower than 30.00% of the control group , the difference was statistically significant (P < 0.05). Conclusion Based on the treatment of elderly hypertensive patients with benazepril combined with amlodipine, traditional Chinese medicine treatment can significantly improve the condition of patients, reduce the incidence of adverse reactions, and has high safety.