〔Abstract〕 Objective To explore the application of timeliness analysis in emergency thrombolysis of ischemic stroke. Methods A total of 90 patients with ischemic stroke admitted to the Second Hospital of Longyan from November 2019 to December 2019 were divided into control group and observation group by computer software, with 45 cases in each group. The control group was treated with ward thrombolysis, and the observation group was treated with emergency thrombolysis by aging analysis, and the indexes of the two groups were compared. Results There was no significant difference in the score of living ability between the two groups before intervention (P > 0.05). Three months after intervention, the living ability score of the observation group was lower than that of the control group, and the difference was statistically significant (P < 0.05). The aging time in the observation group was shorter than that in the control group at different stages, and the difference was statistically significant (P < 0.05). Before intervention, there was no significant difference in neurological function scores between the two groups (P > 0.05). After 7 and 14 days of intervention, the neurological function score of the observation group was lower than that of the control group, the difference was statistically significant (P < 0.05). Conclusion The application of timeliness analysis in emergency thrombolysis of ischemic stroke can improve the neurological function and living ability of patients and shorten the time of each stage of emergency thrombolysis.