〔Abstract〕 Objective To study the clinical effect of percutaneous neuromuscular electrical stimulation in the treatment of peripheral nerve injury. Methods A total of 62 patients with peripheral nerve injury who were admitted to Guangzhou First People's Hospital from January 2020 to May 2021 were selected and divided into control group and observation group according to the principle of random number table, with 31 cases in each group. The control group was given routine treatment, and the observation group was given transcutaneous neuromuscular electrical stimulation on the basis of the control group, and the clinical efficacy of the two treatment methods was compared. Results The total effective rate in the observation group was 93.55%, which was higher than 74.19% in the control group, and the difference was statistically significant (P < 0.05). There was no significant difference in electromyography indexes of median nerve, ulnar nerve and radial nerve between the two groups before treatment (P > 0.05). After treatment, the motor nerve conduction velocity and amplitude of patients in the two groups were higher than those before treatment, and the motor potential latency was shorter than that before treatment, and the motor nerve conduction velocity and amplitude of patients in the observation group were higher than those in the control group, and the motor potential latency was shorter than that in the control group, the differences were statistically significant (P < 0.05). Conclusion The overall effect of percutaneous neuromuscular electrical stimulation for peripheral nerve injury is significant.