〔Abstract〕 Objective To explore and analyze the diagnostic value of fetal heart rate monitor combined with color Doppler ultrasound in fetal distress. Methods 100 parturients who delivered in the First Hospital of Sanming from October 2019 to May 2020 were selected, and their clinical data were analyzed retrospectively, and they were divided into two groups based on the Apgar score of the newborn, namely the distress group (Apgar score < 7, 49 cases) and healthy group (Apgar score ≥ 7, 51 cases), both groups were diagnosed with fetal heart rate monitor combined with color Doppler ultrasound. The umbilical artery blood flow resistance index (RI), pulsatility index (PI), peak systolic blood flow velocity (S), end diastolic blood flow velocity (D), S/D ratio and S/D at different stages of labor were observed and recorded. Results The RI, PI and S/D in the distress group were higher than those in the healthy group at different stages of pregnancy, and the differences were statistically significant (P ＜ 0.05). The S/D of different stages of labor in the distress group was significantly higher than that of the healthy group, the difference was statistically significant (P < 0.05). Conclusion The clinical application of fetal heart rate monitor combined with color Doppler ultrasound diagnosis for parturients can provide accurate guidance for the diagnosis of fetal distress symptoms in time by monitoring the fetal heart rate and monitoring the blood flow of the umbilical artery, and can better avoid the occurrence of adverse outcomes.