Abstract:〔Abstract〕 Objective To explore the role of spinal puncture and epidural block technology in labor analgesia. Methods 350 cases of painless laber admitted to Yangjiang Maternity and Child Health Hospital from January 2019 to December 2020 were selected as the study subjects, and were randomly divided into epidural anesthesia (EP) group of 50 cases and dural puncture epidural 300 cases in the block (DPE) group and 300 pregnant women in the DPE group were randomly divided into two groups: 150 cases in group A (for administration concentration) and 150 cases in group B (for indwelling epidural catheter length). 150 pregnant women in group A were randomly divided into three groups: 150 cases in group A1 (0.065% ropivacaine), 50 cases in group A2 (0.08% ropivacaine), and 50 cases in group A3 (0.1% ropivacaine). 150 pregnant women in group B were randomly divided into three groups: 50 cases in group B1 (indwelling length of 3 cm), 50 cases in group B2 (indwelling length of 4 cm), and 50 cases in group B3 (indwelling length of 5 cm). Compare the labor process of different mothers time, delivery outcome and Apgar score of newborns. Results The natural delivery rate of all women in the DPE group was higher than that in the EP group (P < 0.05). There was no statistically significant difference in the way of delivery of observation objects such as A1, A2, A3, B1, B2, B3 in the DPE group (P > 0.05); the time of the first stage of labor and the second stage of labor of all women in the DPE group was significantly shorter than that of EP in the group, the 1-min Apgar score of newborns was significantly lower than EP (P < 0.05). There was no significant difference of the 5 min Apgar score of newborns between the DPE group and EP group (P > 0.05). Comparison of the first stage of labor time, the second stage of labor time, newborn 1min Apgar score, newborn 5min Apgar score in groups A1, A2, A3, B1, B2, B3, and other observation subjects, showed no significantly significant difference (P > 0.05). Conclusion DPE is a more safe and painless delivery technique. It has a better blocking effect on the sacral nerve and a faster onset of action. It can ensure the safety of the parturient, different anesthesia application methods will not have a direct impact on the delivery safety of patients.