〔Abstract〕 The Cloud class platform adopted the online and offline blended teaching mode to construct the innovative course teaching system of diagnostics of traditional Chinese medicine (TCM), which hands over the initiative in the classroom to students, so as to improve the shortcomings in traditional teaching, such as the rigid teaching mode, the lack of practice, the shortage of resources and so on. The Cloud class teaching could effectively solved problems that the theoretical knowledge system of diagnostics of TCM is too huge for students to master. It can also make the knowledge fragmented so that the students can choose learning time combined with teaching videos independently and carry on study comb through practices, which could improve the efficiency of learning. In addition, teachers can conduct targeted guidance and analysis through the feedback on learning results to clarify misunderstandings in a timely manner. The combination of online and offline teaching based on Cloud class provides students with a broader space and more free time. It has a certain application value in the teaching of diagnostics of TCM in colleges and universities.