〔Abstract〕 Objective To analyze the application effect of blood cell test quality control in clinical medical tests. MethodsSelect 200 healthy people who were examined in Yueyang First People's Hospital from February 2018 to February 2019 as the research subjects. The blood samples of 200 healthy people were tested under different conditions, and the results of blood cell test were analyzed. Analysis of influencing factors. Results Under different anticoagulant conditions, the white blood cells (WBC), red blood cells (RBC), platelets (PLT) and hemoglobin (HGB) in the blood samples of the 1:10000 anticoagulant group were all higher than the 1:5000 anticoagulant. In the coagulant group, the difference was statistically significant (P < 0.05); under different storage time conditions, the WBC, RBC, PLT and HGB indexes in the samples placed in the 4 h group were higher than those in the 30 min group, and the difference was statistically significant (P < 0.05); Under different temperature conditions, WBC, RBC and PLT in blood samples of low temperature group were higher than that of room temperature group, and HGB was lower than that of room temperature group, the difference was statistically significant (P < 0.05). Conclusion During the blood cell test, the proportion of anticoagulant, the time of sample placement, and the temperature will affect the test results of the sample. The test personnel and medical personnel should actively control each test link.