〔Abstract〕 Objective To compare the diagnostic value for intracranial aneurysm using multiple row spiral computer layer imaging angiography (CTA) diagnosis and X-ray digital subtraction angiography (DSA) diagnosis. Methods 84 intracranial aneurysm patients treated by Yellow River Central Hospital from March 2013 to March 2019 were selected as the research data, and all performed multiple spiral CTA examination and DSA examination, analyzed the imaging data, and compared the detection rate and excellent imaging quality of the two diagnostic methods. Results 92 aneurysms were observed in 84 patients with multiple spiral CTA, diameters are between 3 and 24 mm, 86 aneurysms could be observed by DSA diagnosis, Diameters are between 2.6 and 22 mm, among them, the aneurysm rate of multiple spiral CTA was 97.87%, significantly higher than the DSA detection rate of 90.43%, the difference was statistical significant (P < 0.05); the excellent imaging quality of multiple row spiral CTA tumors accounted for 70.65%, the superior tumor imaging quality of DSA diagnosis accounted for 47.83%, the comparative differences were significant, the difference was statistically significant (P < 0.05). Conclusion The diagnosis of multiple spiral CTA, simple operation, high image quality, easy to be accepted by patients and high clinical diagnostic value.