〔Abstract〕 Objective To analyze the effect of different surgical timings on the treatment effect of different selections of surgical timing in the process of surgical repair of the wounds of patients with high-voltage electrical burns of the wrist. Methods From November 2018 to November 2019, 100 patients with wrist high-voltage electrical burns admitted to the Department of Burns and Plastic Surgery of Loudi First People's Hospital were selected as the research objects, and they were divided into two groups according to the timing of the operation. There were 50 cases in the control group and 50 cases in the observation group. Patients in the control group were treated with flap repair after other treatments, and patients in the observation group were treated with flap repair on the day of injury. The clinical treatment effects of the two groups of patients were compared. Results The operation time, flap transplantation area, and hospitalization time of the observation group were better than those of the control group, and the difference was statistically significant (P < 0.05); in terms of area after debridement, there was no statistically significant difference between the groups (P > 0.05). In terms of patient recovery, the observation group was better than the control group in terms of radial nerve, ulnar nerve, median nerve, middle wrist flexion ability, and flexor tendon function, and the difference was statistically significant (P < 0.05). Conclusion In the process of repairing skin flaps for patients with high-voltage electrical burns of the wrist, the operation is carried out as soon as possible, which is of positive value for the optimization of the patient's surgical indicators and functional recovery.