〔Abstract〕 Objective To explore the influencing factors and intervention Methods of treatment delay in patients with acute myocardial infarction (AMI) in primary chest pain center. Methods A total of 120 PATIENTS with AMI admitted to the Chest Pain Center of Qingcheng District People's Hospital of Qingyuan from July 2018 to June 2020 were selected as the research objects. The influencing factors of treatment delay were analyzed by Logistic multivariate regression analysis, and the corresponding countermeasures were formulated. Results Age, onset time, diabetes, educational level, residential area, medical decision and reperfusion strategy were independent risk factors for delay time of prehospital and hospital treatment. Conclusions In the practical clinical work, it is important to optimize the treatment process of elderly patients with AMI, diabetic patients and living in rural areas, select an appropriate reperfusion strategy, shorten the transport time of patients needing PCI and reduce the total time of myocardial ischemia.