〔Abstract〕 Objective To investigate the relationship between type 2 diabetes mellitus (T2DM) and coronary arterycalcification and cardiovascular and cerebrovascular events. Methods A total of 100 T2DM patients admitted to The First Hospital of Nanchang city from August 2015 to May 2018 were selected as subjects. All patients underwent 64-slice spiral computed tomography (CT). The incidence of coronary artery calcification and cardiovascular and cerebrovascular events in T2DM patients was analyzed, and the incidence of cardiovascular and cerebrovascular events in patients with different degrees of coronary artery calcification was compared. Results Among 100 T2DM patients, 67 cases (67.00 %) had calcification, including 42 cases (42.00 %) with mild calcification, 15 cases (15.00 %) with moderate calcification, 10 cases (10.00 %) with severe calcification, 19 cases (19.00 %) with cardiovascular and cerebrovascular events. With the aggravation of coronary artery calcification, the incidence of cardiovascular and cerebrovascular events gradually increased, and the difference was statistically significant (P < 0.05). Logistic regression analysis showed that T2DM and calcification score were independent risk factors for cardiovascular and cerebrovascular events. Conclusion T2DM is prone to coronary artery calcification and cardiovascular and cerebrovascular events, and T2DM and calcification score are independent risk factors for cardiovascular and cerebrovascular events.