〔Abstract〕 Objective Explore the factors that affect the achievement of the international normalized ratio (INR) in patients with warfarin anticoagulation therapy. Method From January 2019 to May 2021, 300 discharged patients from Zhongshan People’s Hospital who received warfarin anticoagulation therapy were surveyed for general information, medical history, follow-up, etc. Questionnaire surveys were conducted, and whether the INR value reached the standard was used as the dependent variable to analyze the patient's Warfare Infl uencing factors of INR value in Lin anticoagulation treatment. Result Among the 300 patients, 169 cases did not meet the INR value, and 131 cases reached the target, with a compliance rate of 43.67%; single factor analysis showed that age, education level, economic income, ethnic genes, patient medication compliance, history of cerebral infarction, Whether the pharmacist is instructed outside the hospital is the infl uencing factor of the INR value in the anticoagulation treatment of warfarin; the results of multivariate logistic regression analysis show that age, education level, patient compliance with medication, ethnic genes, and out-of-hospital guidance of the pharmacist indicate that the INR value in the warfarin anticoagulation treatment of the patient is not Independent factors infl uencing compliance. Conclusion In patients applying warfarin anticoagulation therapy, the INR value compliance is related to age, education level, ethnic genes, medication compliance, and out-of-hospital interventions by pharmacists. It is necessary to strengthen targeted health guidance out-of-hospital by pharmacists to ensure the quality of anticoagulation treatment.