〔Abstract〕 Objective To analyze the etiological characteristics of related lung infections after airway stent placement, and to summarize anti-infection strategies. Methods From February 2017 to December 2020, 54 patients with pulmonary infection after airway stent implantation treated in Quanzhou First Hospital affi liated to Fujian Medical University were randomly selected as the research object, and their clinical data were retrospectively reviewed Analyze and analyze the types of pathogenic bacteria cultured by the microorganisms of the lower respiratory tract secretions of patients and the results of drug sensitivity tests. Results The results of the microbial culture of the lower respiratory tract secretions of the patients showed that all patients were positive in 54 cases (100.00%), and a total of 65 pathogenic bacteria were isolated; among them, the isolation rate of Pseudomonas aeruginosa was the highest, followed by golden grapes. 20.00% of cocci, 1.54% of hemolytic staphylococci, and 1.54% of Candida parapsilosis are the lowest; Staphylococcus aureus is resistant to erythromycin, penicillin G, clindamycin, amikacin, etc., and is resistant to teicoplanin, Compound trimethoprim, vancomycin, oxacillin, linezolid, cefazolin, etc. are more sensitive; Pseudomonas aeruginosa is resistant to meropenem, cefazolin, levofl oxacin, netilmicin, etc., Escherichia coli The bacteria are resistant to gentamicin, imipenem, tazobactam sodium, and meropenem. Conclusion After patients undergoing airway stent implantation, the risk of related lung infections is higher, and the pathogenic bacteria of lung infections are mainly Gram-negative bacteria. The clinical treatment staff should combine the results of pathogen culture and the patient's Physiological and pathological conditions, some treatment procedures are optimized to reduce the incidence of postoperative related pneumonia.