rTMS 联合言语训练治疗脑卒中后失语症的临床研究
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(1. 华中科技大学协和深圳医院,广东 深圳 518052;2. 湖南中医药大学,湖南 长沙 410208;3. 深圳市第二 人民医院,广东 深圳 518035)

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王桂喜,男,主管技师,主要研究方向是脑卒中神经康复。

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广东省医学科研基金项目资助课题(A2016171);广东省医学科研基金项目广东卫生健康适宜技术 课题(202006181153333000);深圳市南山区技术研发和创意设计项目分项资金教育(卫生)科技 资助项目(南科研卫 2018083 号);深圳市第二人民医院临床研究项目资助课题(20200601016-FS01)


Clinical Study of rTMS Combined with Speech Training in the Treatment of Aphasia after Stroke
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(1.Huazhong University of Science and Technology Union Shenzhen Hospital, 518052; 2.Hunan University of Chinese Medicine,410208; 3.Shenzhen Second people’s Hospital, 518035)

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    摘要:

    〔摘 要〕 目的:研究重复经颅磁刺激(rTMS)治疗脑卒中后失语症患者的临床效果,促进脑卒中后失语症康复诊疗技 术规范化。方法:选取华中科技大学协和深圳医院康复医学科住院病房 2018 年 12 月至 2020 年 10 月收治的 26 例脑卒中后 失语症患者,按随机数字表法分为对照组(14 例)与观察组(12 例)。观察组采用 rTMS 联合言语康复训练治疗,对照组 采用常规言语康复训练治疗。在治疗前后对患者采用西方成套失语症量表(WAB)、改良波士顿诊断性失语症检查(BDAE) 进行评分,比较两组患者治疗前后的临床差异。结果:治疗后,观察组疗效高于对照组;两组患者西方成套失语症量表 (WAB)评分均较治疗前明显改善,观察组改善情况优于对照组,差异均具有统计学意义(P < 0.05)。两组改良波士顿 诊断性失语症检查(BDAE)等级均比治疗前提高,且观察组患者的改善情况优于对照组,差异具有统计学意义(P < 0.05)。 结论:rTMS 联合言语康复训练治疗脑卒中后失语症能有效提高患者的谈话、理解、复述、命名等能力,改善患者语言沟通 能力,提高患者日常生活能力,改善患者的生活质量。

    Abstract:

    〔Abstract〕 Objective To study the clinical effect of repeated transcranial magnetic stimulation (rTMS) in the treatment of aphasia after stroke, and to promote the standardization of rehabilitation and diagnosis of aphasia after stroke. Methods From December 2018 to October 2020, 26 patients with aphasia after stroke who met the inclusion criteria of this study were selected, and the patients were divided into control group (14 cases) and treatment group (12cases) by random number table method. The treatment group was treated with rTMS combined with speech rehabilitation training, while the control group was treated with conventional speech rehabilitation training. Patients in each group were treated once a day, 5 times a week for 2 weeks. Before and after treatment, patients were scored by Western Complete Aphasia Scale (WAB) and modified Boston Diagnostic Aphasia Test (BDAE), and the clinical differences between the two groups were compared before and after treatment. Results The scores of Western Complete Aphasia Scale (WAB) were improved signifi cantly in both groups. The difference between the two groups was statistically signifi cant (P < 0.05). The modifi ed Boston diagnostic aphasia test (BDAE) was improved.After treatment, there was a statistically signifi cant difference in the increase of BDAE grade between the two groups (P < 0.05). Conclusion RTMS combined with speech rehabilitation training in the treatment of post-stroke aphasia can effectively improve the ability of conversation, understanding, retelling and naming, improve the ability of language communication, improve the ability of daily living and improve the quality of life of patients.

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  • 收稿日期:2021-01-20
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  • 在线发布日期: 2021-11-19
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