〔Abstract〕 ObjectiveTo analyze the value of diffusion tensor imaging (DTI) for prognostic rehabilitation of cerebral infarction in the subacute phase. Methods 96 patients with subacute cerebral infarction in Dapeng New District Nan'ao People's Hospital of Shenzhen from March 2020 to October 2020 were selected as the research objects, all of them were divided into groups according to the treatment. 52 cured patients were classifi ed as group A, and 32 patients with improved condition were classifi ed as group B. Twelve patients with signifi cant improvement were classifi ed as group C, and all study subjects were selected from January 2018 to January 2020. All three groups of patients were tested by DTI technology, and the examination conditions of the three groups of patients were compared and analyzed. Results DTI technology detects the affected side and found that on DCavg and Exat, group A is lower than group B and C, group B is better than group C (P < 0.05); on FA and VRA, group A is higher than group B and group C, and group B is better Group C (P < 0.05). DTI technology detected the healthy side and found that there was little difference between the three groups on DCavg, FA, VRA and Exat (P > 0.05). Conclusion The DTI technique has ideal effects in the subacute phase of cerebral infarction, can accurately assess the prognosis and rehabilitation of patients, and can be further promoted in clinical practice.