〔Abstract〕 Objective To analyze the application effect of coronary CTA in cardiovascular diseases. Methods From June 2017 to February 2018,188 patients with suspected coronary artery stenosis or coronary heart disease admitted to Zhengzhou Yihe hospital were taken as research objects. All patients underwent coronary CTA and DSA examination. DSA examination was taken as the gold standard.The results of coronary CTA examination were compared with the gold standard to evaluate the diagnostic value of CTA. Results A total of 145 of 188 suspected patients with cardiovascular diseases were confi rmed as cardiovascular diseases by DSA examination,143 cases of cardiovascular diseases were detected by coronary CTA examination, of which 5 cases were misdiagnosed and 3 cases were misdiagnosed. Taking DSA examination as the gold standard, the specifi city, accuracy, sensitivity, positive predictive value and negative predictive value of coronary CTA in diagnosing cardiovascular diseases are 91.30%, 96.81%, 98.59%, 96.55% and 97.67 % respectively. Conclusion Coronary CTA examination to diagnose cardiovascular disease has the advantages of simple operation, low examination cost, and non-invasiveness, and has higher accuracy, sensitivity and specifi city in the identifi cation of cardiovascular diseases, which can provide a strong diagnostic basis for clinical treatment.